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The WHO Covid-19 Research Database is a resource created in response to the Public Health Emergency of International Concern (PHEIC). Its content remains searchable and spans the time period March 2020 to June 2023. Since June 2023, manual updates to the database have been discontinued.

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Comparison of nine different commercially available molecular assays for detection of SARS-CoV-2 RNA.

Eberle, Ute; Wimmer, Clara; Huber, Ingrid; Neubauer-Juric, Antonie; Valenza, Giuseppe; Ackermann, Nikolaus; Sing, Andreas.

Eur J Clin Microbiol Infect Dis ; 40(6): 1303-1308, 2021 Jun.

Article in English | MEDLINE | ID: covidwho-1053012

ABSTRACT

To face the COVID-19 pandemic, the need for fast and reliable diagnostic assays for the detection of SARS-CoV-2 is immense. We describe our laboratory experiences evaluating nine commercially available real-time RT-PCR assays. We found that assays differed considerably in performance and validation before routine use is mandatory.

Subject(s)

COVID-19 Nucleic Acid Testing/standards , COVID-19 Testing/methods , COVID-19/diagnosis , RNA, Viral/isolation & purification , Humans , Molecular Diagnostic Techniques/standards , Reagent Kits, Diagnostic/standards , Real-Time Polymerase Chain Reaction/standards , SARS-CoV-2

ABSTRACT

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